News A closer look at the in-cheek delivery landscape Key insights from our review article Giving medications in a way that’s easier and more pleasant, like via the cheek, is what the BUCCAL-PEP project is all about. There is strong momentum in this research field, with many research groups now focusing on this route of […]
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From innovative dosage forms to alternative administration routes, the 5th European Conference on Pharmaceutics – held on 24–25 March 2025 in Porto – was a showcase of forward-thinking in modern therapeutics.
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This week, the BUCCAL-PEP consortium gathered at the University of Aveiro, to discuss the progress of developing the BUCCAL-PEP film.
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News Special delivery – Prof. David Brayden featured in The Medical Independent Can peptides be delivered through the cheek? That’s the intriguing question Prof. David Brayden tackled in his recent talk at the UCD Charles Institute Derma Seminar series. As the project coordinator of BUCCAL-PEP, he explored a cutting-edge approach to peptide drug delivery –
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News Exploring the optimal materials for the BUCCAL-PEP film What if, instead of taking a tablets or injections, you could just place a small, dissolvable film inside your cheek to take your medication? That’s what the BUCCAL-PEP project is working on. This in-cheek approach, also known as buccal delivery, is particularly helpful for elderly, children,
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News Rewatch Prof. David Brayden’s talk at the Charles Institute Seminar Series On Thursday, October 31st 2024, our Project Coordinator Prof. David Brayden presented the BUCCAL-PEP project during the Charles Institute Seminar Series. Buccal and sub-lingual epithelia have been used for decades as administration site for small molecules in the form of tablets, lozenges, and
Rewatch Prof. David Brayden’s talk at the Charles Institute Seminar Series Read More »
On Thursday, October 31st 2024, the Charles Institute Seminar Series will take place. Our Project Coordinator Prof. David Brayden will present the BUCCAL-PEP project during this seminar. The Charles Institute Seminar Series 🗣️ Creating devices to administer macromoleculesvia the Buccal Epithelium: The EU BUCCAL-PEP consortium By Prof. David Brayden, Ph.D., FAAPS, MRIAProfessor of Advanced Drug
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📢 BUCCAL-PEP attends the CÚRAM, SFI Research Centre for Medical Devices Summit at the University of Galway! 👉 Last month, project members Sandeep Karki and Dr. Sahil Malhotra represented BUCCAL-PEP on all 3 days of the CÚRAM Summit in Galway, standing as the 10th anniversary celebration of CÚRAM. They participated in the event’s extensive program,
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We are thrilled to share that we have a new partner added to our BUCCAL-PEP consortium. Since March 1st, the University of Aveiro located in Aveiro Portugal, has been part of our consortium. Together with the BUCCAL-PEP partners, they were awarded the Hop-On grant. The University of Aveiro will contribute to the consortium by employing polysaccharide-based biomaterials with
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The World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, held in Vienna, brought together professionals from industry and academia to exchange insights and research discoveries. Various topics were covered, spanning from drug delivery methods to manufacturing techniques. BUCCAL-PEP members Nazanin Zanjanizadeh Ezazi and Eleftheria Pantazoglou from DTU presented their work on the BUCCAL-PEP project through
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This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant number 101071054. Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or European Innovation Council. Neither the European Union nor the granting authority can be held responsible for them.
Susie lives in Dublin and volunteers her time to help advocate for others who live with obesity and Type 2 Diabetes. Most recently Susie was involved with Diabetes Ireland in the drafting of the “Talking about Diabetes : Language Matters” Guide. Addressing stigma for either Diabetes or Obesity which Susie has lived experience of, is high on the list of her priorities and being involved in advisory boards is one example of how to do this by being involved throughout the research process from beginning to end.
Maura thinks it is important to treat the patient holistically. Over the years, she has been visiting several hospitals for different conditions, and these silos can be exhausting. She is passionate about learning about obesity since she discovered that it is a disease in 2019. Prior to that, her self-blame and stigma held her back. She has learned that obesity is a gateway to other diseases, and she knows this firsthand because she lives with Type 2 Diabetes, Hypertension, Gout, Fluid Retention, and Osteoarthritis. She attends a Chronic Disease Clinic in Ballina every six months, which has thankfully eliminated the silo appointments to three different hospitals and their various departments.
Mary Frances is married with one adult child. She has worked for many years as a Social Care worker within Adult services for those with intellectual disabilities. She is SAM’s trained as she dispenses medication on a daily basis (SAM’s = Safe Administering of Medication).
She is also one of the first committee members and a patient representative for an ICPO. They give talks to medical students of many disciplines regarding respect and dignity for people living with obesity. They also hold weekly support meetings and face-to-face meetings when possible. The subject of medications that are becoming available for those who are living with obesity is very topical at present.
Dr. Javier O. Morales is an Associate Professor at the University of Chile, specializing in pharmaceutical science and technology. He heads the Center of New Drugs for Hypertension (CENDHY) and is an Associate Researcher in the Advanced Center for Chronic Diseases (ACCDiS). With a Ph.D. from The University of Texas at Austin, he focuses on innovative drug delivery systems, particularly for peptides, proteins, and poorly water-soluble drugs. His research explores nanoencapsulation and alternative routes of administration. Dr. Morales has a keen interest in buccal absorption and 2D/3D printing for drug delivery. He joined BUCCAL-PEP’s SAB to advance less invasive diabetes treatments and explore synergies with his own research.
Prof. Giovanni Traverso is the Director of the Laboratory for Translational Engineering at MIT and Harvard, an Associate Professor of Mechanical Engineering at MIT, an Associate Physician in Gastroenterology at Brigham and Women’s Hospital, Harvard Medical School, and an Associate Member of the Broad Institute. He received his undergraduate and medical degrees from Cambridge and a PhD from Johns Hopkins, where he pioneered non-invasive cancer detection. His postdoctoral research at MIT focused on advanced drug delivery and gastrointestinal sensing. His current work drives next-generation drug delivery systems and ingestible devices for physiological monitoring.
Prof. Ljiljana Fruk is a Professor of Bionano Engineering at the Department of Chemical Engineering and Biotechnology at University of Cambridge. Her research encompasses the design and development of nanoscale materials for biomedical applications, including design of drug nanocarriers for solid tumours and biosensors for early detection of cancer. She is particularly interested in development of nature-inspired structures, and has also made significant contributions to development of hybrid bio-nano materials and their application in photocatalysis and sustainable manufacturing. She is one of the co-founders of Senesys Bio, Cambridge spinout developing therapeutic formulations for senescent cell removal. Prof Fruk is an active science popularizer, art-science curator, and the co-author of the field-establishing Molecular Aesthetics book (MIT Press 2013), and the first textbook on Bionanotechnology (Cambridge University Press 2021).
Dr. Eva Roblegg is a full professor at the University of Graz, specializing in pharmaceutical technology and biopharmacy. She leads the Drug Delivery and Advanced Manufacturing group and focuses on the development of nano drug delivery systems (nanoDDS) for the treatment of oral diseases, such as oral mucositis. To better understand the relationship between nanoDDS and buccal/sublingual tissues, her group has developed in vitro cell and tissue models that mimic healthy and inflamed human oral mucosa. Eva Roblegg works closely with the Research Center Pharmaceutical Engineering, a center of excellence in Graz, Austria, where she is involved in advanced technologies for the continuous manufacturing and conversion of (nano-)drug delivery systems into final dosage forms. Given her research interest in this area and the opportunity to create further synergies with her own research, she has joined BUCCAL-PEP’s SAB.
Dr. Andrew Muddle, founder and former CEO of MedPharm, brings over 30 years of pharmaceutical industry experience in drug delivery. He played a pivotal role in PowderJect Pharmaceuticals plc’s early development and IPO, and his career includes positions at Elan Corporation, Ethical Pharmaceuticals Ltd (U.K.), Controlled Therapeutics (Scotland), and Ciba-Geigy (now Novartis). Dr. Muddle excels in managing projects to commercialization, specializing in transdermal and topical products. He joined BUCCAL-PEP due to the challenge of oral peptide delivery.
