On Thursday, October 31st 2024, our Project Coordinator Prof. David Brayden presented the BUCCAL-PEP project during the Charles Institute Seminar Series. 

Buccal and sub-lingual epithelia have been used for decades as administration site for small molecules in the form of tablets, lozenges, and dissolvable films. They achieve blood levels quickly and avoid the liver first pass effect, a major advantage over oral administration.

The BUCCAL-PEP EU consortium addresses a new question as to whether we can now administer peptides via these oro mucosal routes? The multiple areas involved include patch and film synthesis, permeation enhancers, peptide selection, use of large animal models, and patient involvement.

📽️ Watch the full recording of the seminar here. >