In-cheek delivery of
peptide-analogue therapies
About Buccal-pep
What we do
Delivering peptide-analogues (large molecules used in medicine) orally is a big problem for pharmaceutical researchers. Only five peptide-analogues have been made into tablets or capsules for oral delivery, but they all have difficulties like low bioavailability (how much of the drug gets into the body), controlling the dosage, inconvenient patient administration, and food interactions.
To solve these problems, the BUCCAL-PEP group will work together to create a patch made of biomaterials that can be placed in the cheek to deliver peptide-analogue treatments. This patch will be the first of its kind and will overcome these difficulties by combining a permeation enhancer (SDC) with biomaterials and a peptide-analogue.
Co-creation
For patients
At BUCCAL-PEP, patients are our top priority. We believe that our technology will improve their quality of life and reduce the burden of their condition. That’s why we’re actively involving patients in our work from the beginning, ensuring that their needs and requirements are considered throughout the development process. By working together with patients, we’re creating a technology that is both effective and user-friendly, with the potential to revolutionize the way peptide drugs are delivered.
Our updates
News
The Charles Institute Seminar Series with Prof. David Brayden
On Thursday, October 31st 2024, the Charles Institute Seminar Series will take place. Our Project Coordinator Prof. David Brayden will present the BUCCAL-PEP project during
BUCCAL-PEP at the CÚRAM Summit!
📢 BUCCAL-PEP attends the CÚRAM, SFI Research Centre for Medical Devices Summit at the University of Galway! 👉 Last month, project members Sandeep Karki and
BUCCAL-PEP’s New Partner!
We are thrilled to share that we have a new partner added to our BUCCAL-PEP consortium. Since March 1st, the University of Aveiro located in Aveiro Portugal,
